Description
ZOXY CR 12.5 mg is a controlled‑release oral tablet containing Paroxetine Hydrochloride, a selective serotonin reuptake inhibitor (SSRI). It is primarily used for the management of depression, anxiety disorders, panic disorder, obsessive-compulsive disorder (OCD), and related mood disorders.
The controlled‑release (CR) formulation ensures the medicine is released gradually into the bloodstream, maintaining stable drug levels throughout the day. This helps enhance therapeutic effectiveness while minimizing side effects, such as nausea or drowsiness, commonly associated with immediate-release formulations.
Mechanism of Action: Paroxetine works by increasing serotonin levels in the brain, a neurotransmitter that plays a key role in regulating mood, anxiety, and emotional balance. This helps improve mood, reduce anxiety, and alleviate obsessive or panic symptoms.
Key Uses:
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Major depressive disorder
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Generalized anxiety disorder
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Panic disorder
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Obsessive-compulsive disorder (OCD)
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Social anxiety disorder
Dosage & Administration:
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Typically taken once daily, with or without food.
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Tablets should be swallowed whole; do not crush or chew to maintain the controlled-release property.
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Dose adjustment may be required based on the patient’s condition, age, and response to treatment.
Precautions:
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Not recommended during pregnancy or breastfeeding unless advised by a doctor.
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May interact with other medications such as MAO inhibitors, anticoagulants, or other SSRIs.
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Abrupt discontinuation can cause withdrawal symptoms; tapering under medical supervision is advised.
Side Effects (Common):
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Nausea, headache, drowsiness, dizziness
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Dry mouth, constipation, or sweating
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Rare but serious: serotonin syndrome, mood changes, or suicidal thoughts

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