ZOVAL 400 MG Tablet – Description

Active Ingredient: Sofosbuvir 400 mg (a direct-acting antiviral agent).

Pharmaceutical Class: Antiviral medicine; specifically a nucleotide analogue inhibitor targeting hepatitis C virus replication.

Mechanism of Action: Sofosbuvir works by interfering with the NS5B RNA-dependent RNA polymerase, a key enzyme that the hepatitis C virus (HCV) uses to copy its genetic material. By acting as a chain terminator during viral RNA synthesis, it disrupts the virus’s ability to replicate and spread within the liver.

Primary Use: Treatment of chronic hepatitis C virus (HCV) infection in adults. Like other sofosbuvir-based therapies, it is typically used as part of a combination antiviral regimen (often with drugs such as ribavirin, ledipasvir, or velpatasvir) to achieve sustained virologic response (SVR) and reduce viral load.

Dosage Form and Strength: Film-coated tablet, 400 mg. Prescribed orally once daily, with or without food, under the guidance of a qualified physician.

Clinical Considerations:

Sofosbuvir is not generally recommended as monotherapy; its effectiveness is optimized in combination with other antivirals depending on the HCV genotype and patient condition.
Treatment duration and specific regimens depend on viral genotype, liver health, and prior treatment history.

Common Side Effects: Patients may report gastrointestinal symptoms (nausea, decreased appetite), fatigue, headache, or general malaise. More severe reactions can occur and should be evaluated promptly by a healthcare provider.

Prescription Requirement: ZOVAL 400 mg is a prescription-only medication. A qualified clinician should determine its use, dosage, and therapy duration.

Storage: Store in a cool, dry place away from direct light and moisture, out of reach of children.

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